That.
With main 99 combats and then go 99 Agility, 99 Thieving, 99 WC. 99 Fishing, 99 Mining, and 99 fletching. Then from there do what you want, I just named some of the skills that you can do without having to transfer money and can do 24/7 without ANY breaks.
Skiller is self explanatory, I don't suggest it if your doing main.
Pure do 85+ str, 94 magic, 99 ranged, 60 attack and whatever prayer you want then go to wild with c'bow to claws. And also barrage on occasion
For staker do about 80 defense, 75 strength, 60 attack, and stake your heart out
For 10b, I suggest you do smaller amounts at a time.
If you were to do all of these accounts at the same time (GL with RAM reqs.), you could make 10b in about 5-6 months.