It was featured in Oprah years ago about this feeling of a person that is inborn like a woman who really feels like a man trapped in a woman's body. I forgot the term sorry. So it is possible. However being homosexual according to psychology and we have discussed that during college, is a gender preference. It means that it is not a disease nor an abnormality but the will to choose someone from the same gender/sex. I am a lesbian and I am proud of it. I never regret nor am I ashamed to admit that. Why? It's because it is my choice and it is what I feel and I never hurt anybody nor abuse anyone because of this. I enhance my talents and share my knowledge and work hard so in the society I can say that I am contributing something even in my own simple way.